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Natural Alternative to NSAIDs (Ibuprofen, Naproxen, Aspirin)

Nonsteroidal anti-inflammatory drugs (NSAIDs) are ubiquitously used across the United States to fight inflammation, pain and fever. According to a review in The American Journal of Managed Care, $4.8 billion is spent on prescription NSAIDs alone, with approximately 35% of people 65 years or older taking a dose every day (1). With more than 20 over the counter options, and 70 million prescriptions written every year, the average consumer doesn’t think twice before taking a dose of NSAIDs. Although NSAIDs are relatively diverse in terms of chemical structure and properties, they all have the same mechanism of action, inhibiting the function of proteins that typically promote inflammation. At a high level, this seems straightforward. When looking deeper, one of the inflammation promoting proteins targeted by NSAIDs also functions in protecting the stomach from its own acid. When NSAIDs (such as aspirin, ibuprofen, and naproxen) are used for extended periods of time, ulcers and internal bleeding can occur. Additionally, the FDA recently strengthened their warning concerning NSAIDs and heart health, saying that non-aspirin NSAIDs can increase the risk of heart attacks or strokes (2).

With the accumulating warnings concerning the harmful side effects of NSAIDs, many medical professionals and consumers are looking for natural alternatives to the synthetic drugs they are accustomed to. One such alternative that is currently being explored by medical professionals is Innerzyme Pain & Inflammation Blend, a comprehensive blend of proteolytic enzymes, herbs and bioflavonoids. It is a full spectrum systemic enzyme specially formulated with bromelain, turmeric, pancreatin, papain, trypsin, chymotrypsin, white willow bark and rutin. Bromelain is a natural enzyme found in pineapples that have been used for hundreds of years to combat inflammation and indigestion. A 2015 report in the International Journal for Surgery found that in rats, bromelain applied to rats significantly reduced inflammation levels in an abdominal surgery model (3). Even more encouraging was the finding that there were no adverse effects on the animals.

Pain and Inflammation BlendTurmeric is a natural compound that is receiving much attention in the inflammation field. While turmeric (curcumin) has long been used as a spice, it’s becoming clear that it has many more roles in human health, other than making our food tasty. Scientists are beginning to decipher the many positive effects seen with turmeric supplementation such as reduced pain and inflammation (ongoing human clinical trials), as well as potential anti-cancer activity in certain animal models. With the ongoing health and safety concerns surrounding the long-term use of NSAIDs, there is now much excitement amongst medical professionals who are having great success administering Innerzyme as a safe, natural and effective alternative for patients. The founder of The Hammer Institute for Anti-Aging Medicine, Eli Hammer, MD says, “I have used systemic enzymes extensively in my practice along with taking them personally for a few years, seeing dramatic reductions in pain and inflammation, and therefore, significant improvements in quality of life. Of all the systemic enzyme brands on the market, I truly believe Innerzyme has finally optimized the proper enzyme blend, while also vastly improving upon the delivery system for better efficacy and ease of administration.”

Many medical professionals are realizing the promising benefits of natural treatment options, as well as preventative care using natural anti-inflammatory products like Innerzyme Pain & Inflammation Blend. Current and future research is expected to further support the use of these natural products as safe and effective alternatives to NSAIDs.

For more information about Innerzyme Pain & Inflammation Blend, click here.


  1. Michael Fine, “Quantifying the Impact of NSAID-Associated Adverse EventsAm J Manag Care 19(14):267-72 (2013).
  2. FDA Drug Safety Communication: FDA strengthens warning that non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) can cause heart attacks or strokesU.S. Food and Drug Administration (7-9-2015).
  3. Sahbaz et. al.,Bromelain: A natural proteolytic for intra-abdominal adhesion preventionInt J Surg 14:7-11 (2015).
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Health Risks From Ibuprofen Use

Innerzyme Pain & Inflammation Blend, a Safe, Natural & Effective Alternative for Pain and Inflammation, Systemic Enzyme Formula

Before you take Ibuprofen again, you should know the health risks!

According to the article, “For Athletes, Risks From Ibuprofen Use” in The New York Times by Gretchen Reynolds, “many active people use the painkiller ibuprofen on an almost daily basis.” Whether an athlete is looking to kill the pain following a strenuous workout or thinking about preventative care from muscle soreness, it is clear that the risks of Ibuprofen are much higher than the benefits these athletes are hoping to experience.

Gretchen Reynolds states, “a valuable new study joins growing evidence that ibuprofen and similar anti-inflammatory painkillers taken before a workout do not offer any benefit and may be causing disagreeable physical damage instead, particularly to the intestines.” She later says, “the most common side-effect of ibuprofen is gastrointestinal damage.”

To read the full article: For Athletes, Risks From Ibuprofen Use by Gretchen Reynolds on December 5, 2012 (The New York Times)

Innerzyme Pain & Inflammation Blend offers a safe, natural, and effective alternative to reduce pain and inflammation following strenuous workouts or sports injuries without any harmful side effects.

Innerzyme’s proprietary blend contains Pancreatin, Papain, Bromelain, Trypsin, Chymotrypsin, Rutin, White Willow Bark and Turmeric root. It is specially formulated to naturally reduce pain, inflammation, excess fibrin and the buildup of excess free radicals.

P&I_FrontThe delivery system for Innerzyme’s Pain & Inflammation Blend is an enteric coated tablet. The enteric coating protects the enzymes from premature release in the acidic region of the stomach allowing maximum absorption and optimal release of the proprietary blend in the pancreatic juices. High potency, minimal dosage with maximum benefit! When taken on an empty stomach, it is believed that enzymes may help manage inflammation by supporting healthy blood flow to the irritated area.

Bromelain is most notable for its effectiveness in the reduction of inflammation and decreasing swelling, but the scope of its benefits continues to increase.* Derived from the pineapple fruit, this natural anti-inflammatory has many health benefits.

Chymotrypsin is naturally produced by the pancreas in the human body. The primary uses of chymotrypsin are as a naturally anti-inflammatory and as a digestive aid. As a natural anti-inflammatory, chymotrypsin may help reduce tissue damage and the formation of fibrin clots during inflammation.*

Turmeric is an herb, an Indian spice that has been used for many years because of its natural medicinal properties. Turmeric is rich in antioxidants and is a powerful anti-inflammatory.

Rutin is a potent bioflavonoid which are water-soluble plant pigments, naturally occurring chemical compounds important to maintaining optimal health. They support health by protecting and strengthening capillaries, help prevent bruising and provide support for many other biological functions.*

For more information about Innerzyme’s Pain & Inflammation Blend, visit:
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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